Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 50002423
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase p51/p66 after 10 to 20 mins in presence of [3H]-TTP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33953(dihydroxy benzoyl naphthyl hydrazone (DHBNH))copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase p51/p66 after 10 to 20 mins in presence of [3H]-TTP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148760(CHEMBL3142914 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50458413(CHEMBL3142917)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148763(CHEMBL3142918 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148764(CHEMBL3142919 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50458414(CHEMBL4211455)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50458414(CHEMBL4211455)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase HMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33953(dihydroxy benzoyl naphthyl hydrazone (DHBNH))copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase p51/p66 after 10 to 20 mins in presence of [3H]-TTP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase HMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50458413(CHEMBL3142917)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of TSAO resistant HIV1 3B reverse transcriptase E138K mutant using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148764(CHEMBL3142919 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of TSAO resistant HIV1 3B reverse transcriptase E138K mutant using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148763(CHEMBL3142918 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of TSAO resistant HIV1 3B reverse transcriptase E138K mutant using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148760(CHEMBL3142914 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of TSAO resistant HIV1 3B reverse transcriptase E138K mutant using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed