Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50002444
TargetProtein delta homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50458549(CHEMBL4207983)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of DLK (unknown origin) using myelin basic protein as substrate preincubated for 15 mins measured after 30 mins in presence of [gamma-32P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50458548(CHEMBL4218417)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK3 KD expressed in baculovirus using myelin basic protein as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50458548(CHEMBL4218417)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant GST-tagged human MLK1 KD (1 to 500 residues) expressed in baculovirus using myelin basic protein as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK3 KD expressed in baculovirus using myelin basic protein as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant GST-tagged human MLK1 KD (1 to 500 residues) expressed in baculovirus using myelin basic protein as substrate preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50458548(CHEMBL4218417)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK2 KD/LZ expressed in baculovirus using myelin basic protein as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK2 KD/LZ expressed in baculovirus using myelin basic protein as substrate preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of DLK (unknown origin) using myelin basic protein as substrate preincubated for 15 mins measured after 30 mins in presence of [gamma-32P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50458548(CHEMBL4218417)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of DLK (unknown origin) using myelin basic protein as substrate preincubated for 15 mins measured after 30 mins in presence of [gamma-32P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed