Compile Data Set for Download or QSAR
Found 43 Enz. Inhib. hit(s) with all data for entry = 50002468
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022520(CHEMBL3349395 | H2N-Abu-Pro-Phe-Abu-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi: <1nMpH: 4.0Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50227343(CHEMBL3349391)copy SMILEScopy InChI
Affinity DataKi: <1nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0 (time-dependent inhibition, T1/2>30 s)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022512(CHEMBL3349394 | Ibu-His-Pro-Phe-Ala-Sta-Leu-PheNH2)copy SMILEScopy InChI
Affinity DataKi:  4nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022507(CHEMBL3349407 | H2N-His-Pro-Phe-His-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  8nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022520(CHEMBL3349395 | H2N-Abu-Pro-Phe-Abu-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  9nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022517(CHEMBL3349397 | POA-Leu-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  12nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022519(CHEMBL3349393 | Ibu-His-Pro-Phe-His-Sta-Leu-PheNH2)copy SMILEScopy InChI
Affinity DataKi:  16nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022519(CHEMBL3349393 | Ibu-His-Pro-Phe-His-Sta-Leu-PheNH2)copy SMILEScopy InChI
Affinity DataKi:  23nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022507(CHEMBL3349407 | H2N-His-Pro-Phe-His-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  34nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022517(CHEMBL3349397 | POA-Leu-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  35nMpH: 4.0Assay Description:Inhibition of rabbit liver cathepsin D at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022515(CHEMBL3349396 | POA-His-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  67nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022512(CHEMBL3349394 | Ibu-His-Pro-Phe-Ala-Sta-Leu-PheNH2)copy SMILEScopy InChI
Affinity DataKi:  99nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022513(CHEMBL3349389 | H2N-Phe-Gly-His-(S,S)-Sta-Ala-Phe-...)copy SMILEScopy InChI
Affinity DataKi:  150nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022515(CHEMBL3349396 | POA-His-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022517(CHEMBL3349397 | POA-Leu-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMpH: 7.4Assay Description:Inhibition of human renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022515(CHEMBL3349396 | POA-His-Sta-Leu-PheOMe)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMpH: 4.0Assay Description:Inhibition of rabbit liver cathepsin D at pH 4.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022523(CHEMBL347185 | H2N-Phe-Gly-His-Nph-Phe-Ala-Phe-OMe)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMpH: 4.0Assay Description:Inhibition of porcine pepsin at pH 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Bos taurus)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022518(CHEMBL407670 | Pro-His-Pro-Phe-His-Leu-CH2NH-Val-I...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 3.3Assay Description:Inhibition of bovine cathepsin D at pH 3.3(no inhibition)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022521(Boc-Phe-His-Cha-CH2-S-Leu-NHCO(CH2)2C6H5 | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 1.9Assay Description:Inhibition of porcine pepsin at pH 1.9More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022518(CHEMBL407670 | Pro-His-Pro-Phe-His-Leu-CH2NH-Val-I...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.0Assay Description:Inhibition of human renin at pH 7.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Bos taurus)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022521(Boc-Phe-His-Cha-CH2-S-Leu-NHCO(CH2)2C6H5 | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 3.2Assay Description:Inhibition of bovine cathepsin D at pH 3.1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.0Assay Description:Inhibition of human renin at pH 7.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 6.0Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50025903(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50025903(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 6.0Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Bos taurus)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 3.2Assay Description:Inhibition of human pepsin at pH 3.1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022508(Boc-Pro-Phe-NMe-His-Leu-OHCH2-Val-Ile-Amp | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022509(Boc-Phe-Phe-Sta-Ala-Sta-OMe | CHEMBL3349390)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Bos taurus)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 3.2Assay Description:Inhibition of bovine cathepsin D at pH 3.1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A-5(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMpH: 3.1Assay Description:Inhibition of human pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022511(Boc-Trp-His-Sta-Ala-Sta-OMe | CHEMBL3349392)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A-5(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 3.1Assay Description:Inhibition of bovine cathepsin D at pH 3.2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetCathepsin D(Bos taurus)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022508(Boc-Pro-Phe-NMe-His-Leu-OHCH2-Val-Ile-Amp | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMpH: 3.2Assay Description:Inhibition of bovine cathepsin D at pH 3.2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022508(Boc-Pro-Phe-NMe-His-Leu-OHCH2-Val-Ile-Amp | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022521(Boc-Phe-His-Cha-CH2-S-Leu-NHCO(CH2)2C6H5 | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50421761(CHEMBL2311113)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022509(Boc-Phe-Phe-Sta-Ala-Sta-OMe | CHEMBL3349390)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetRenin(Homo sapiens (Human))
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022516(Boc-Trp-Trp-Sta-Ala-Sta-OMe | CHEMBL3142766)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.4Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50421761(CHEMBL2311113)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022516(Boc-Trp-Trp-Sta-Ala-Sta-OMe | CHEMBL3142766)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022511(Boc-Trp-His-Sta-Ala-Sta-OMe | CHEMBL3349392)copy SMILEScopy InChI
Affinity DataIC50: 850nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50025903(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed
TargetPepsin A(Porcine)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50025903(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 2.0Assay Description:Inhibition of porcine pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85742PubMed