Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50002659
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023505(2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023495(2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023500((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023496(2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023505(2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023496(2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023495(2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023499((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023493(CHEMBL266267 | sec-Butyl-(9-chloro-2-furan-2-yl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023499((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023503(9-Chloro-2-thiophen-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023506(9-Chloro-2-furan-3-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023494(9-Benzyloxy-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023493(CHEMBL266267 | sec-Butyl-(9-chloro-2-furan-2-yl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023500((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023506(9-Chloro-2-furan-3-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 295nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023503(9-Chloro-2-thiophen-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 324nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023498(2-(5-Bromo-furan-2-yl)-9-chloro-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 531nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023501(9-Chloro-2-(1H-pyrrol-2-yl)-[1,2,4]triazolo[1,5-c]...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023497(9-Chloro-2-(tetrahydro-furan-2-yl)-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 827nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023501(9-Chloro-2-(1H-pyrrol-2-yl)-[1,2,4]triazolo[1,5-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023491(2-Furan-2-yl-6-methyl-6H-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023494(9-Benzyloxy-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023498(2-(5-Bromo-furan-2-yl)-9-chloro-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023497(9-Chloro-2-(tetrahydro-furan-2-yl)-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023491(2-Furan-2-yl-6-methyl-6H-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008874(9-Chloro-2-furan-2-yl-6H-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023490(CHEMBL7582 | tert-Butyl-(9-chloro-2-furan-2-yl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023502((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008874(9-Chloro-2-furan-2-yl-6H-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023502((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50023490(CHEMBL7582 | tert-Butyl-(9-chloro-2-furan-2-yl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed