Compile Data Set for Download or QSAR
Found 193 Enz. Inhib. hit(s) with all data for entry = 50002768
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462718(CHEMBL4237479)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462710(CHEMBL4251324)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462711(CHEMBL4241204)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462716(CHEMBL4240949)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50097154(CHEMBL3581121)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462715(CHEMBL4241689)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462712(CHEMBL4249314)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462714(CHEMBL4241299)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462717(CHEMBL4248852)copy SMILEScopy InChI
Affinity DataKi:  430nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462713(CHEMBL4242549)copy SMILEScopy InChI
Affinity DataKi:  510nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462713(CHEMBL4242549)copy SMILEScopy InChI
Affinity DataKi:  580nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50097154(CHEMBL3581121)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462718(CHEMBL4237479)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462711(CHEMBL4241204)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462717(CHEMBL4248852)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462716(CHEMBL4240949)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462715(CHEMBL4241689)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462714(CHEMBL4241299)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462710(CHEMBL4251324)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462712(CHEMBL4249314)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKAalpha (1 to 351 residues) (unknown origin) using Leu-Arg-Arg-Ala-Ser-Leu-Gly as substrate by pyruvate kinase-lactate dehydrogenase c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462710(CHEMBL4251324)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR isolated from human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR isolated from human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Bcr-Abl (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Bcr-Abl (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MINK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IRR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PHK-gamma2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetTyrosine-protein kinase Fer(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PASK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MST1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT-4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NEK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetInsulin receptor(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MAPKAPK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
TargetSerine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PAK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77MHPubMed
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