Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with all data for entry = 50002838
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Evaluated for the inhibition of thymidylate synthesis in intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023902(2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023902(2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024475(2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024474(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024475(2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024474(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024471(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024470(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024472(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024470(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024472(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024475(2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024471(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024475(2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+6nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed