Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 50002895
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  252nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as free enzyme after 1 hr in presence of ss-RNA P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  1.54E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as free enzyme after 1 hr in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  1.58E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as enzyme-substrate complex after 1 hr in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  4.33E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as enzyme-substrate complex after 1 hr in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464490(CHEMBL4282493)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV3 full length NS5 RdRp assessed as decrease in dsRNA levels preincubated for 20 mins followed by ss-RNA and ATTO-CTP, ATP, GTP and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464494(CHEMBL4292407)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464502(CHEMBL4281417)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464498(CHEMBL4279581)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464511(CHEMBL4289289)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464508(CHEMBL4284511)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464495(CHEMBL4281097)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464512(CHEMBL4284513)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464489(CHEMBL4281094)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464491(CHEMBL4295172)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464506(CHEMBL4280007)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464507(CHEMBL4289005)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464496(CHEMBL4291308)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464505(CHEMBL3233235)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464501(CHEMBL3233241)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464493(CHEMBL4277678)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464500(CHEMBL2326938)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464492(CHEMBL4291731)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464503(CHEMBL4287909)copy SMILEScopy InChI
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464504(CHEMBL4277265)copy SMILEScopy InChI
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464509(CHEMBL4280662)copy SMILEScopy InChI
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464497(CHEMBL4287912)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464510(CHEMBL4287491)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to DENV3 NT-647-NHS labeled NS5 RdRp after 1 hr by microscale thermophoresis methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed