Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 50003185
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Inhibition of recombinant human CA12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human CA6 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant human CA13 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Inhibition of recombinant human CA14 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant human CA12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human CA5b preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of recombinant human CA5a preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  98nMAssay Description:Inhibition of recombinant human CA6 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  126nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  172nMAssay Description:Inhibition of recombinant human CA13 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  677nMAssay Description:Inhibition of recombinant human CA14 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  922nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  939nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  1.43E+3nMAssay Description:Inhibition of recombinant human CA5a preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi:  5.33E+3nMAssay Description:Inhibition of recombinant human CA5b preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M8KPubMedDrugBank