TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged human AXL cytoplasmic domain (464 to 885 end residues) expressed in baculovirus expression system using fluorecen...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged human TRKA cytoplasmic domain (436 to 790 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of N-terminal GST-tagged human TYRO3 cytoplasmic domain (453 to 890 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of N-terminal GST-tagged human TRKA cytoplasmic domain (436 to 790 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetNT-3 growth factor receptor(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of N-terminal GST-tagged human TRKC cytoplasmic domain (456 to 825 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of N-terminal GST-tagged full length human QIK (1 to 926 end residues) expressed in baculovirus expression system using fluorecence-labele...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of N-terminal GST-tagged human TYRO3 cytoplasmic domain (453 to 890 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of N-terminal GST-tagged full length human SLK (1 to 1152 end residues) expressed in baculovirus expression system using fluorecence-label...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged full length human NuaK1 (1 to 661 end residues) expressed in baculovirus expression system using fluorecence-labe...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of N-terminal GST-tagged human KIT cytoplasmic domain (544 to 976 end residues) expressed in baculovirus expression system using fluorecen...More data for this Ligand-Target Pair
TargetNT-3 growth factor receptor(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of N-terminal GST-tagged human TRKC cytoplasmic domain (456 to 825 end residues) expressed in baculovirus expression system using fluorece...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair