Compile Data Set for Download or QSAR
Found 42 Enz. Inhib. hit(s) with all data for entry = 50003458
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0150nMAssay Description:Apparent binding affinity against estradiol-stimulated T-47D cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataKi:  0.0160nMAssay Description:Apparent binding affinity against estradiol-stimulated T-47D cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataKi:  0.0230nMAssay Description:Stimulation of alkaline phosphatase activity in human endometrial Ishikawa cells with 1 nM E2 estradiolMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471256(CHEMBL291808)copy SMILEScopy InChI
Affinity DataKi:  0.0280nMAssay Description:Apparent binding affinity against estradiol-stimulated T-47D cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0420nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0470nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0690nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 2.5%DMFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0760nMAssay Description:Apparent inhibition constant for estrogen receptor in Human Breast cancer cytosol in 2.5%DMFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Apparent binding affinity against estradiol-stimulated ZR-75-1-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  0.113nMAssay Description:Apparent inhibition constant for estrogen receptor in Human Breast cancer cytosol in 2.5%DMFMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM20625(4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | ...)copy SMILEScopy InChI
Affinity DataKi:  0.126nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM20625(4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | ...)copy SMILEScopy InChI
Affinity DataKi:  0.128nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  0.138nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  0.181nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 2.5%DMFMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)copy SMILEScopy InChI
Affinity DataKi:  0.249nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)copy SMILEScopy InChI
Affinity DataKi:  0.346nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471258(CHEMBL67783)copy SMILEScopy InChI
Affinity DataKi:  0.525nMAssay Description:Apparent binding affinity against estradiol-stimulated T-47D cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)copy SMILEScopy InChI
Affinity DataKi:  0.668nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 2.5%DMFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)copy SMILEScopy InChI
Affinity DataKi:  0.755nMAssay Description:Apparent inhibition constant for estrogen receptor in Human Breast cancer cytosol in 2.5%DMFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Apparent inhibition constant for estrogen receptor in Human Breast cancer cytosol in 2.5%DMFMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 2.5%DMFMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471257(CHEMBL67837)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471257(CHEMBL67837)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471253(CHEMBL441622)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Apparent binding affinity against estradiol-stimulated T-47D cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)copy SMILEScopy InChI
Affinity DataKi:  7.60nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Apparent inhibition constant for estrogen receptor in Human uterine cytosol in 3.3%ethanolMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471253(CHEMBL441622)copy SMILEScopy InChI
Affinity DataKi: >270nMAssay Description:Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471256(CHEMBL291808)copy SMILEScopy InChI
Affinity DataIC50: 0.243nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471255(Acolbifene | EM-652 | SCH-57068)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of estradiol-stimulated ZR-75-1-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471254(CHEMBL308234)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Stimulation of alkaline phosphatase activity in human endometrial Ishikawa cells with 1 nM E2 estradiolMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471258(CHEMBL67783)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471257(CHEMBL67837)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471257(CHEMBL67837)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of estradiol-stimulated ZR-75-1-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Le Centre Hospitalier Universitaire de Qu£bec

Curated by ChEMBL
LigandPNGBDBM50471253(CHEMBL441622)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of estradiol-stimulated T-47D cell proliferation.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DKCPubMed