Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 50004885
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029559(2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029577(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029561((2-{2-[1-(3-Fluoro-benzyl)-4-methyl-6-(5-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029564(CHEMBL341562 | {2-[1-(4-Chloro-benzyl)-4-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029568(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029573(2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029570(CHEMBL139891 | {2-[1-(4-Chloro-benzyl)-4-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029576((2-{2-[1-(3-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029560(2-[1-(4-Chloro-benzyl)-6-(5-methoxy-pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029567(2-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029569((2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029563(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029571((2-{2-[1-(4-Fluoro-benzyl)-4-methyl-6-(5-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029572(2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029558(2-[1-(4-Chloro-benzyl)-4-methyl-6-(quinolin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029558(2-[1-(4-Chloro-benzyl)-4-methyl-6-(quinolin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029562(CHEMBL140915 | {2-[1-(3-Chloro-benzyl)-4-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029562(CHEMBL140915 | {2-[1-(3-Chloro-benzyl)-4-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029570(CHEMBL139891 | {2-[1-(4-Chloro-benzyl)-4-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029566(5-Chloro-2-{2-[1-(4-chloro-benzyl)-4-methyl-6-(5-p...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029574(3-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029565(2-[1-(4-Chloro-benzyl)-6-(isoquinolin-3-ylmethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029575(2-{2-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029560(2-[1-(4-Chloro-benzyl)-6-(5-methoxy-pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029567(2-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029565(2-[1-(4-Chloro-benzyl)-6-(isoquinolin-3-ylmethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029559(2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53JW5PubMed