Compile Data Set for Download or QSAR
Found 39 Enz. Inhib. hit(s) with all data for entry = 50005112
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)copy SMILEScopy InChI
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to cat Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032958(CHEMBL430501 | [3-Amino-2-(4-chloro-phenyl)-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032969(CHEMBL321255 | [3-Amino-2-(4-chloro-phenyl)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032968((3-Amino-propyl)-difluoromethyl-phosphinic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032971((3-Amino-1-methyl-propyl)-methyl-phosphinic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032971((3-Amino-1-methyl-propyl)-methyl-phosphinic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 166nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to cat Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032961((3-Amino-2-hydroxy-propyl)-difluoromethyl-phosphin...)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032962(((Z)-3-Amino-propenyl)-phosphinic acid | CGP38593 ...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032959(CHEMBL111378 | [3-Amino-2-(4-fluoro-phenyl)-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032970((3-Amino-butyl)-phosphinic acid | CHEMBL113907)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032973(((Z)-3-Amino-propenyl)-methyl-phosphinic acid | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 665nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032975((3-Amino-2-methyl-propyl)-phosphinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032977((3-Amino-2-phenyl-propyl)-phosphinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032967((3-Amino-1-methyl-propyl)-phosphinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032979((3-Amino-propyl)-hydroxymethyl-phosphinic acid | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032966((3-Amino-1-hydroxy-propyl)-methyl-phosphinic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032972((3-Amino-propyl)-ethyl-phosphinic acid | CGP-36216...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032963((S)-4-Amino-3-(4-chloro-phenyl)-butyric acid | BAC...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032972((3-Amino-propyl)-ethyl-phosphinic acid | CGP-36216...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032962(((Z)-3-Amino-propenyl)-phosphinic acid | CGP38593 ...)copy SMILEScopy InChI
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032981((3-Amino-propyl)-phosphonic acid | CHEMBL286077 | ...)copy SMILEScopy InChI
Affinity DataIC50: 6.81E+3nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032965(((R)-3-Amino-2-hydroxy-butyl)-phosphinic acid | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032973(((Z)-3-Amino-propenyl)-methyl-phosphinic acid | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032974((3-Amino-1-ethyl-propyl)-methyl-phosphinic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
CIBA-GEIGY AG

Curated by ChEMBL
LigandPNGBDBM50032960((3-Amino-1-trifluoromethyl-propyl)-methyl-phosphin...)copy SMILEScopy InChI
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58KDPPubMed