Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for entry = 50005974
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50017896((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50017896((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50017896((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043282(2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50017896((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043282(2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50017896((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043283(2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043283(2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human microsomeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043283(2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human microsomeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043283(2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043283(2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043282(2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043282(2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human microsomeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50043282(2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GBKPubMed