Compile Data Set for Download or QSAR
Found 45 Enz. Inhib. hit(s) with all data for entry = 50006004
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043670(2-{(S)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043682((R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043669(6-[3-Fluoro-5-((S)-1-methoxy-1-thiazol-2-yl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043666((R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043678((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50000829(6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043671(6-[3-Fluoro-5-((R)-1-methoxy-1-methoxymethyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50407160(CHEMBL2092747)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043681(4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043665(6-[3-(4-Acetyl-tetrahydro-pyran-4-yl)-phenoxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043666((R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043668(6-[3-(4-Ethyl-tetrahydro-pyran-4-yl)-phenoxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043683(6-[3-(4-Methoxymethyl-tetrahydro-pyran-4-yl)-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043672(6-[3-Fluoro-5-((R)-1-methoxy-1-thiazol-2-yl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043682((R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043678((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043669(6-[3-Fluoro-5-((S)-1-methoxy-1-thiazol-2-yl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043664(1-Methyl-6-[3-(4-methyl-tetrahydro-pyran-4-yl)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043667(2-{(R)-1-Methoxy-1-[2-methyl-3-(naphthalen-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043673(2-{(R)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 513nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043671(6-[3-Fluoro-5-((R)-1-methoxy-1-methoxymethyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007055(4-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043670(2-{(S)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043679(6-[3-Fluoro-5-(4-hydroxy-tetrahydro-pyran-4-yl)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory concentration of the compound against 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50407159(CHEMBL2092993)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043684(6-[3-(4-Hydroxymethyl-tetrahydro-pyran-4-yl)-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043672(6-[3-Fluoro-5-((R)-1-methoxy-1-thiazol-2-yl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007054(5-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043680(4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043673(2-{(R)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007046(2-(3-Methoxy-indan-5-yloxymethyl)-naphthalene | CH...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50000826(2-{1-Methoxy-1-[2-methyl-5-(naphthalen-2-ylmethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007045(2-[1-Methoxy-4-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007061(2-[6-(Naphthalen-2-ylmethoxy)-indan-1-yl]-thiazole...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CZPPubMed