Compile Data Set for Download or QSAR
Found 34 Enz. Inhib. hit(s) with all data for entry = 50006364
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499195(CHEMBL3735504)copy SMILEScopy InChI
Affinity DataKi:  0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499203(CHEMBL3736036)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499205(CHEMBL3734814)copy SMILEScopy InChI
Affinity DataKi:  0.480nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499208(CHEMBL3734872)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499197(CHEMBL3736465)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499206(CHEMBL3735949)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499198(CHEMBL3736278)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499199(CHEMBL3735673)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499202(CHEMBL3735523)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499200(CHEMBL3735044)copy SMILEScopy InChI
Affinity DataKi:  6.40nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499210(CHEMBL3734846)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499211(CHEMBL3735247)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499204(CHEMBL3735719)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499201(CHEMBL3736469)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499207(CHEMBL3735975)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499197(CHEMBL3736465)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499199(CHEMBL3735673)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499199(CHEMBL3735673)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499209(CHEMBL3735096)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499203(CHEMBL3736036)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499203(CHEMBL3736036)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499204(CHEMBL3735719)copy SMILEScopy InChI
Affinity DataKi:  374nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499198(CHEMBL3736278)copy SMILEScopy InChI
Affinity DataKi:  608nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499197(CHEMBL3736465)copy SMILEScopy InChI
Affinity DataKi:  700nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499204(CHEMBL3735719)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499205(CHEMBL3734814)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499198(CHEMBL3736278)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499195(CHEMBL3735504)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50184719(CHEMBL208116 | N-(5-fluoro-1H-benzo[d]imidazol-2-y...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499196(CHEMBL3735448)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50499196(CHEMBL3735448)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JG8PubMed