Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with all data for entry = 50006695
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502562(CHEMBL4469066)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502563(CHEMBL4471659)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502565(CHEMBL4462369)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502566(CHEMBL4438626)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502564(CHEMBL4558495)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502567(CHEMBL4469343)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502568(CHEMBL4591167)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502568(CHEMBL4591167)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502564(CHEMBL4558495)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502562(CHEMBL4469066)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine chloride as substrate incubated for 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502563(CHEMBL4471659)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502567(CHEMBL4469343)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502566(CHEMBL4438626)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed
TargetCholinesterase(Homo sapiens (Human))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50502565(CHEMBL4462369)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55RRDPubMed