Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 50007139
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK5/p35 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2/CyclinE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50309910(CHEMBL608154 | ML-120B | N-(6-chloro-7-methoxy-9H-...)copy SMILEScopy InChI
Affinity DataIC50: 465nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 911nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetAurora kinase B(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK14 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Eppley Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B39PubMed