Compile Data Set for Download or QSAR
Found 52 Enz. Inhib. hit(s) with all data for entry = 50007389
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT6 receptor expressed in CHOK1 cells measured after 60 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50458225(Ciproxifan)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)copy SMILEScopy InChI
Affinity DataKi:  76nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataKi:  84nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508998(CHEMBL3747907)copy SMILEScopy InChI
Affinity DataKi:  128nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50509001(CHEMBL4552323)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-LSD from recombinant human 5HT6 receptor expressed in CHOK1 cells measured after 60 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50053441(CHEMBL3323053)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508995(CHEMBL4591636)copy SMILEScopy InChI
Affinity DataKi:  3.53E+4nMAssay Description:Inhibition of alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508995(CHEMBL4591636)copy SMILEScopy InChI
Affinity DataKi:  6.68E+4nMAssay Description:Inhibition of alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508992(CHEMBL4470517)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of COX2 in lympho-monocytes (unknown origin) preincubated for 30 mins followed by LPS challenged measured after 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508996(CHEMBL4464476)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Inhibition of 5HTT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508994(CHEMBL4589118)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508996(CHEMBL4464476)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of human MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of human MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50509001(CHEMBL4552323)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508991(CHEMBL4566976)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50509000(CHEMBL4446093)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of COX2 in lympho-monocytes (unknown origin) preincubated for 30 mins followed by LPS challenged measured after 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508995(CHEMBL4591636)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508999(CHEMBL4445674)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of MOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508997(CHEMBL4538181)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508991(CHEMBL4566976)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50458225(Ciproxifan)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508991(CHEMBL4566976)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of M1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508995(CHEMBL4591636)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508996(CHEMBL4464476)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of rat BChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508998(CHEMBL3747907)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508993(CHEMBL4545210)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50053441(CHEMBL3323053)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508997(CHEMBL4538181)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Equus caballus (Horse))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of equine BChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508999(CHEMBL4445674)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508999(CHEMBL4445674)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50458225(Ciproxifan)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508992(CHEMBL4470517)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of COX1 in human platelets after 30 mins by mass spectrometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508993(CHEMBL4545210)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes at -60 mV holding potential by two-electrode voltage-clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50509000(CHEMBL4446093)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of COX1 in human platelets after 30 mins by mass spectrometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508997(CHEMBL4538181)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50508991(CHEMBL4566976)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using EVNLDAEF as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50458225(Ciproxifan)copy SMILEScopy InChI
Affinity DataIC50: 7.73E+4nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University of W£rzburg

Curated by ChEMBL
LigandPNGBDBM50458225(Ciproxifan)copy SMILEScopy InChI
Affinity DataIC50: 8.61E+4nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222Z25PubMed
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