Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for entry = 50007419
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal His-tagged human FPPS (1 to 353 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509177(CHEMBL4515661)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509180(CHEMBL4550027)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509178(CHEMBL4516343)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509183(CHEMBL4534214)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM36510(1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic a...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509174(CHEMBL4467922)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50235478(CHEMBL4100337)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509179(CHEMBL4550499)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509176(CHEMBL4577736)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509181(CHEMBL4448870)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022663(CHEMBL3299047)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50235474(CHEMBL4090167)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509182(CHEMBL4467306)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50509175(CHEMBL4566427)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MJVPubMed