Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50007431
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063243(CHEMBL161499 | N-(2,6-Diisopropyl-phenyl)-2-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063239(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal LAI assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063239(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063226(CHEMBL160149 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063236(CHEMBL159871 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063231(CHEMBL159621 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063220(CHEMBL161270 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063235(CHEMBL161798 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063232(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063229(CHEMBL161292 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063221(CHEMBL161295 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063227(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063239(CHEMBL161638 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase by microsomal MAI2 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063230(CHEMBL159491 | N-(2,6-Diisopropyl-phenyl)-2,2-dime...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063224(CHEMBL159414 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063237(2-Phenyl-N-(2,4,6-trimethoxy-phenyl)-malonamic aci...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063240(CHEMBL161639 | N-(2,6-Diisopropyl-phenyl)-2-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063233(CHEMBL159597 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063234(CHEMBL351398 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063222(CHEMBL159993 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063225(2-Phenyl-N-(2,4,6-triisopropyl-phenyl)-malonamic a...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063245(CHEMBL159694 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063238(2-Pyridin-2-yl-N-(2,4,6-triisopropyl-phenyl)-malon...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063223(CHEMBL159374 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063228(CHEMBL161102 | N-(2,6-Diisopropyl-phenyl)-2-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063242(CHEMBL350951 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063244(CHEMBL162298 | N-(2,6-Diisopropyl-phenyl)-2,2-dime...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50063241(CHEMBL159680 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051R8PubMed