Compile Data Set for Download or QSAR
Found 75 Enz. Inhib. hit(s) with all data for entry = 50007541
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human JAK3 kinase-domain using Biotin-Lyn-Substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510276(CHEMBL4440795)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510272(CHEMBL4524343)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510275(CHEMBL4453064)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510273(CHEMBL4583532)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Tyk2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510265(CHEMBL4456396)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human JAK1 kinase-domain using Biotin-Lyn-Substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510266(CHEMBL4521339)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510263(CHEMBL4449906)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human TYK2 kinase domain using biotin-IRS1-substrate as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 kinase-domain using Biotin-Lyn-Substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant epitope tagged JAK2 kinase domain (828 to 1132 residues) (unknown origin) using peptide substrate by fluorescence based ass...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510274(CHEMBL4464597)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant epitope tagged JAK1 kinase domain (837 to 1142 residues) (unknown origin) using peptide substrate by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of JAK1 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510268(CHEMBL4524537)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | US10961228, Example ABT-494 | U...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510277(CHEMBL4471390)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510271(CHEMBL4552039)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510278(CHEMBL4466925)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510267(CHEMBL4569551)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510276(CHEMBL4440795)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510262(CHEMBL4549680)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510270(CHEMBL4537207)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510268(CHEMBL4524537)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510272(CHEMBL4524343)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510269(CHEMBL4462728)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510271(CHEMBL4552039)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant epitope tagged Tyk2 kinase domain (873 to 1187 residues) (unknown origin) using peptide substrate by fluorescence based ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of Tyk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510266(CHEMBL4521339)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510263(CHEMBL4449906)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510278(CHEMBL4466925)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510273(CHEMBL4583532)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510277(CHEMBL4471390)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510264(CHEMBL4452803)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510274(CHEMBL4464597)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510276(CHEMBL4440795)copy SMILEScopy InChI
Affinity DataIC50: 141nMAssay Description:Inhibition of JAK2 in human TF-1 cells assessed as reduction in GM-CSF-induced cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510261(CHEMBL4590082)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Inhibition of JAK2 in human TF-1 cells assessed as reduction in GM-CSF-induced cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510275(CHEMBL4453064)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of JAK3 in human HT-2 cells assessed as reduction in IL-2-induced cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8W5BPubMed
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