Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50007661
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511349(CHEMBL4475494 | US10988478, Example 139)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511360(CHEMBL4556091)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511362(CHEMBL4466981 | US10988478, Example 256)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511358(CHEMBL4472406 | US10988478, Example 175)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511359(CHEMBL4545898 | US10988478, Example 258)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511366(CHEMBL4568894)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511361(CHEMBL4445098)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511348(CHEMBL4566431 | US11034698, Example 105)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511357(CHEMBL4452765 | US11034698, Example 92)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511365(CHEMBL4473269 | US10988478, Example 33)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511352(CHEMBL4439292)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511352(CHEMBL4439292)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511363(CHEMBL4536154 | US10988478, Example 289)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511354(CHEMBL4444608 | US10988478, Example 118)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511356(CHEMBL4537890 | US10988478, Example 385)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511355(CHEMBL4464216)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511355(CHEMBL4464216)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511350(CHEMBL4468790 | US10988478, Example 140)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511351(CHEMBL4557715 | US10988478, Example 499)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511347(CHEMBL4592237 | US10988478, Example 401)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511353(CHEMBL4518564 | US11034698, Example 152)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511360(CHEMBL4556091)copy SMILEScopy InChI
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511348(CHEMBL4566431 | US11034698, Example 105)copy SMILEScopy InChI
Affinity DataIC50: 0.0780nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511359(CHEMBL4545898 | US10988478, Example 258)copy SMILEScopy InChI
Affinity DataIC50: 0.0810nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511361(CHEMBL4445098)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511366(CHEMBL4568894)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511358(CHEMBL4472406 | US10988478, Example 175)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511349(CHEMBL4475494 | US10988478, Example 139)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511362(CHEMBL4466981 | US10988478, Example 256)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511350(CHEMBL4468790 | US10988478, Example 140)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511357(CHEMBL4452765 | US11034698, Example 92)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511363(CHEMBL4536154 | US10988478, Example 289)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511365(CHEMBL4473269 | US10988478, Example 33)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511356(CHEMBL4537890 | US10988478, Example 385)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FDMPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511364(CHEMBL4466517 | US10988478, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IFN alpha production preincubated for 90 mins followed by R848 stimul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511364(CHEMBL4466517 | US10988478, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB