Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50007955
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069616((2R,3S)-N*1*-Hydroxy-2-{2-[(E)-hydroxyimino]-2-phe...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069604(CHEMBL118054 | [(2S,3R)-3-((S)-1-Carbamoyl-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069601((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069620((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069608((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069612(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 30-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069603((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069608((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069619(4-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 50-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069621((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-{2-[(E)-methoxyi...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069605((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069603((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069607((2R,3S)-2-Carbamoylmethylsulfanylmethyl-N*4*-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069612(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069600((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*1*...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069617((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-cy...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069609((2R,3S)-2-{2-Biphenyl-4-yl-2-[(E)-hydroxyimino]-et...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069613((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069618((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069611((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069614((2R,3S)-2-(2-Biphenyl-4-yl-2-oxo-ethylsulfanylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069602(CHEMBL440712 | Thioacetic acid S-[(2S,3R)-3-((S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069596((R)-2-Benzyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069605((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069599((R)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069599((R)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069615(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069580((R)-2-Benzyl-N*1*-((S)-1-benzylcarbamoyl-2-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069580((R)-2-Benzyl-N*1*-((S)-1-benzylcarbamoyl-2-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069602(CHEMBL440712 | Thioacetic acid S-[(2S,3R)-3-((S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069611((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069596((R)-2-Benzyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 2000...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed