Compile Data Set for Download or QSAR
Found 37 Enz. Inhib. hit(s) with all data for entry = 50008303
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for the inhibition of human leukocyte elastase(HLE).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 7.03E+4nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed