Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 50008529
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0310nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0640nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0670nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0710nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  0.122nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  0.196nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  60.1nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)copy SMILEScopy InChI
Affinity DataKi:  73.2nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  168nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  188nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  196nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  246nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074092(6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(...)copy SMILEScopy InChI
Affinity DataKi:  246nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50074093((2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080MWPubMed