Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50008596
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075121(5-[(3aS,8aS)-5-(4-Hydroxy-phenyl)-2-oxo-3,3a,8,8a-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075122(5-((3aS,8aS)-2-Oxo-3,3a,8,8a-tetrahydro-2H-indeno[...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075123(4-((3R,3aS,8aS)-2-Oxo-3,3a,8,8a-tetrahydro-2H-inde...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075120(5-[(3R,3aS,8aS)-5-(4-Hydroxy-phenyl)-2-oxo-3,3a,8,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075119(5-[(3aR,8aS)-6-(3-Methoxy-phenyl)-3-methyl-2-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed