Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50008871
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523039(CHEMBL4591338)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM368199((S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523049(CHEMBL4441471)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523050(CHEMBL4455953)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523040(CHEMBL4463541)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523035(CHEMBL4594150)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523057(CHEMBL4447143)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523053(CHEMBL4567402)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523054(CHEMBL4476031)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523062(CHEMBL4450730)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523041(CHEMBL4588281)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50508708(CHEMBL4438260)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523051(CHEMBL4456532)copy SMILEScopy InChI
Affinity DataIC50: 0.420nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523042(CHEMBL4552853)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523038(CHEMBL4470926)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523060(CHEMBL4468700)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523048(CHEMBL4462970)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523059(CHEMBL4586333)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523043(CHEMBL4543969)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523052(CHEMBL4531089)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523046(CHEMBL4534455)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523058(CHEMBL4460089)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523045(CHEMBL4451300)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523047(CHEMBL4437725)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523061(CHEMBL4578130)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523055(CHEMBL4482870)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523044(CHEMBL4476007)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523037(CHEMBL4544038)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523036(CHEMBL4543659)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50523056(CHEMBL4564477)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M3VPubMed