Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for entry = 50008995
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524359(CHEMBL4465674)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524360(CHEMBL3265242)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524355(CHEMBL4467328)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524361(CHEMBL4451258)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524357(CHEMBL4558119)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524354(CHEMBL3265243)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524353(CHEMBL4518549)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524358(CHEMBL4475568)copy SMILEScopy InChI
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524356(CHEMBL4460886)copy SMILEScopy InChI
Affinity DataKi:  1.48E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB