Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 50009058
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079754(CHEMBL65476 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079751(CHEMBL63426 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079757(7-(4-Isopropyl-benzyl)-N*3*,N*3*-dimethyl-7H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079755(7-(4-Isopropyl-benzyl)-3-piperidin-1-yl-7H-pyrrolo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079756(7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079759(CHEMBL305557 | N*3*-Ethyl-7-(4-isopropyl-benzyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 524nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079753(7-(4-Isopropyl-benzyl)-N*3*-methyl-7H-pyrrolo[3,2-...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079749(7-(4-tert-Butyl-benzyl)-7H-pyrrolo[3,2-f]quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079764(7-(4-Isopropyl-benzyl)-N*1*,N*1*,N*3*,N*3*-tetrame...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079758(7-(6-Methyl-naphthalen-2-ylmethyl)-7H-pyrrolo[3,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079762(7-(4-Ethoxy-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079763(7-(4-Isopropyl-benzyl)-N*1*,N*3*,N*3*-trimethyl-7H...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079752(7-(4-Ethyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079761(2-[1-Amino-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079760(7-(4-Methylsulfanyl-benzyl)-7H-pyrrolo[3,2-f]quina...)copy SMILEScopy InChI
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50079750(7-(4-Vinyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,...)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X284BPubMed