Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50009204
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081273((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081256((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081259((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081265((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081252((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081246((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081240(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081243(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081260((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.62nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081261((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081247((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081253((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081239((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081272((S)-5-Acetylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081264((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081249(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081251((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081258(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081262(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081248((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081266((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081267(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081241(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081271((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081270((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081255(6-Benzenesulfonylamino-2-{4-[(2,7-dimethyl-4-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081257((S)-5-Benzoylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081250((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081263((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081254(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081269(4-Acetylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 13.4nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081242(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 14.2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081245((R)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081268(2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 15.4nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081244(4-Benzoylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64XDPubMed
TargetThymidylate synthase(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair