Found 68 Enz. Inhib. hit(s) with all data for entry = 50009511 
Affinity DataIC50: 130nMAssay Description:Displacement of BODIPY TR-ADP from bovine GRK1 (1 to 535 residues) preincubated for 10 mins followed by compound addition and measured after 10 to 15...More data for this Ligand-Target Pair
3D Structure (crystal)TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of bovine GRK1 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine GRK1 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of BODIPY TR-ADP from GRK5 (unknown origin) preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of BODIPY TR-ADP from GRK5 (unknown origin) preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of BODIPY TR-ADP from GRK5 (unknown origin) preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by f...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of BODIPY TR-ADP from human GRK2 preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by fluorescence...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Displacement of BODIPY TR-ADP from human GRK2 preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by fluorescence...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of BODIPY TR-ADP from bovine GRK1 (1 to 535 residues) preincubated for 10 mins followed by compound addition and measured after 10 to 15...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of BODIPY TR-ADP from human GRK2 preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by fluorescence...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 100 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK1 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
