Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for entry = 50009707
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086873(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086875(6-[5-(4-Methyl-piperazine-1-sulfonyl)-2-propoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086872(1-Benzyl-6-[5-(4-methyl-piperazine-1-sulfonyl)-2-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086874(6-(2-Propoxy-phenyl)-3,7-dihydro-imidazo[4,5-g]qui...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed