Compile Data Set for Download or QSAR
Found 61 Enz. Inhib. hit(s) with all data for entry = 50009716
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077244(CHEMBL31815 | N-(4-m-Tolylamino-quinazolin-6-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 0.420nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077238(CHEMBL280757 | N-[4-(3-Bromo-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077235(CHEMBL28418 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077242(CHEMBL31373 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087067(CHEMBL31326 | N-[4-(3-Bromo-phenylamino)-7-(3-diet...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087077(CHEMBL31816 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087081(CHEMBL31570 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.970nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087069(CHEMBL31656 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087078(CHEMBL27688 | N-[7-(3-Morpholin-4-yl-propoxy)-4-m-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087070(CHEMBL32844 | N-{4-(3-Bromo-phenylamino)-7-[3-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087074(CHEMBL32079 | N-{4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087076(CHEMBL27685 | N-[4-(3-Bromo-4-fluoro-phenylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087068(CHEMBL31622 | N-{7-[3-(4-Methyl-piperazin-1-yl)-pr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087066(CHEMBL281543 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077238(CHEMBL280757 | N-[4-(3-Bromo-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087070(CHEMBL32844 | N-{4-(3-Bromo-phenylamino)-7-[3-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087080(CHEMBL286343 | N-[4-(3-Bromo-phenylamino)-7-(3-imi...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077242(CHEMBL31373 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087073(CHEMBL31419 | N-[4-(3-Bromo-phenylamino)-7-(3-morp...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087075(CHEMBL31588 | N-[4-(3-Bromo-phenylamino)-7-(4-dime...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077242(CHEMBL31373 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077244(CHEMBL31815 | N-(4-m-Tolylamino-quinazolin-6-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087076(CHEMBL27685 | N-[4-(3-Bromo-4-fluoro-phenylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087073(CHEMBL31419 | N-[4-(3-Bromo-phenylamino)-7-(3-morp...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087073(CHEMBL31419 | N-[4-(3-Bromo-phenylamino)-7-(3-morp...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087071(CHEMBL284326 | N-{4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077238(CHEMBL280757 | N-[4-(3-Bromo-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087075(CHEMBL31588 | N-[4-(3-Bromo-phenylamino)-7-(4-dime...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087076(CHEMBL27685 | N-[4-(3-Bromo-4-fluoro-phenylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077235(CHEMBL28418 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077235(CHEMBL28418 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087068(CHEMBL31622 | N-{7-[3-(4-Methyl-piperazin-1-yl)-pr...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087072(CHEMBL31630 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087080(CHEMBL286343 | N-[4-(3-Bromo-phenylamino)-7-(3-imi...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077244(CHEMBL31815 | N-(4-m-Tolylamino-quinazolin-6-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087078(CHEMBL27688 | N-[7-(3-Morpholin-4-yl-propoxy)-4-m-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087083(CHEMBL31369 | N-{4-[3-Bromo-4-(2-dimethylamino-eth...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087079(CHEMBL283201 | N-[4-(3-Bromo-4-dimethylaminomethyl...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087072(CHEMBL31630 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087077(CHEMBL31816 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087071(CHEMBL284326 | N-{4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
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