Affinity DataKi: 35nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 238nMAssay Description:Inhibition of [3H]dofetilide binding to human ERG expressed in HEK293 cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of VMAT2 in rat striatal homogenate assessed as reduction in [3H]DA uptake after 8 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of [3H]dofetilide binding to human ERG expressed in HEK293 cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.07E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.08E+3nMAssay Description:Inhibition of [3H]dofetilide binding to human ERG expressed in HEK293 cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.57E+3nMAssay Description:Inhibition of DAT in rat striatal synaptosomes assessed as reduction in [3H]DA uptake preincubated for 5 mins followed by [3H]DA addition measured af...More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measur...More data for this Ligand-Target Pair
Affinity DataKi: 1.59E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 2.58E+3nMAssay Description:Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measur...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 2.94E+3nMAssay Description:Inhibition of [3H]dofetilide binding to human ERG expressed in HEK293 cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.05E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 3.34E+3nMAssay Description:Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measur...More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measur...More data for this Ligand-Target Pair
Affinity DataKi: 3.71E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 3.86E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 4.63E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Inhibition of DAT in rat striatal synaptosomes assessed as reduction in [3H]DA uptake preincubated for 5 mins followed by [3H]DA addition measured af...More data for this Ligand-Target Pair
Affinity DataKi: 6.63E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat whole brain homogenate (excluding cerebellum) after 30 mins by liquid scintillation spectrometric anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.28E+4nMAssay Description:Inhibition of DAT in rat striatal synaptosomes assessed as reduction in [3H]DA uptake preincubated for 5 mins followed by [3H]DA addition measured af...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+4nMAssay Description:Inhibition of DAT in rat striatal synaptosomes assessed as reduction in [3H]DA uptake preincubated for 5 mins followed by [3H]DA addition measured af...More data for this Ligand-Target Pair