Compile Data Set for Download or QSAR
Found 39 Enz. Inhib. hit(s) with all data for entry = 50010116
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535302(CHEMBL4568293)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535306(CHEMBL4552051)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535302(CHEMBL4568293)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535295(CHEMBL4554072)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535298(CHEMBL4438929)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535306(CHEMBL4552051)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535305(CHEMBL4554976)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535296(CHEMBL4516496)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535300(CHEMBL4586884)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535301(CHEMBL4439461)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535298(CHEMBL4438929)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535295(CHEMBL4554072)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535300(CHEMBL4586884)copy SMILEScopy InChI
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535306(CHEMBL4552051)copy SMILEScopy InChI
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535302(CHEMBL4568293)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535295(CHEMBL4554072)copy SMILEScopy InChI
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535301(CHEMBL4439461)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535299(CHEMBL4471251)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535300(CHEMBL4586884)copy SMILEScopy InChI
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535303(CHEMBL4450260)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535299(CHEMBL4471251)copy SMILEScopy InChI
Affinity DataIC50: 5.98E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535301(CHEMBL4439461)copy SMILEScopy InChI
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535305(CHEMBL4554976)copy SMILEScopy InChI
Affinity DataIC50: 9.47E+3nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535298(CHEMBL4438929)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535303(CHEMBL4450260)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535296(CHEMBL4516496)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535297(CHEMBL4555824)copy SMILEScopy InChI
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535297(CHEMBL4555824)copy SMILEScopy InChI
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535299(CHEMBL4471251)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535297(CHEMBL4555824)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535307(CHEMBL4543223)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535308(CHEMBL4583406)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535307(CHEMBL4543223)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535304(CHEMBL4476554)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse brain AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535307(CHEMBL4543223)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50535303(CHEMBL4450260)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human H3R expressed in methylhistamine-induced human H3-bla U2OS cells incubated for 30 mins by beta-lactamase complementation technolo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48JWPubMed