Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 50010121
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535367(CHEMBL4456883)copy SMILEScopy InChI
Affinity DataEC50:  1.09E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535387(CHEMBL4585144)copy SMILEScopy InChI
Affinity DataEC50:  830nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535369(CHEMBL4461163)copy SMILEScopy InChI
Affinity DataEC50:  940nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535370(CHEMBL4448603)copy SMILEScopy InChI
Affinity DataEC50:  810nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535371(CHEMBL4455911)copy SMILEScopy InChI
Affinity DataEC50:  730nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535372(CHEMBL4532035)copy SMILEScopy InChI
Affinity DataEC50:  1.15E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535373(CHEMBL4471591)copy SMILEScopy InChI
Affinity DataEC50:  1.02E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535374(CHEMBL4591348)copy SMILEScopy InChI
Affinity DataEC50:  2.06E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535375(CHEMBL4592387)copy SMILEScopy InChI
Affinity DataEC50:  6.67E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535376(CHEMBL4451432)copy SMILEScopy InChI
Affinity DataEC50:  1.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM21675((4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethy...)copy SMILEScopy InChI
Affinity DataEC50:  500nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535377(CHEMBL4553281)copy SMILEScopy InChI
Affinity DataEC50:  740nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535378(CHEMBL4562865)copy SMILEScopy InChI
Affinity DataEC50:  2.80E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535379(CHEMBL4445722)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535380(CHEMBL4578551)copy SMILEScopy InChI
Affinity DataEC50:  5.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535381(CHEMBL4591419)copy SMILEScopy InChI
Affinity DataEC50:  300nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535382(CHEMBL4588863)copy SMILEScopy InChI
Affinity DataEC50:  460nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535383(CHEMBL4436469)copy SMILEScopy InChI
Affinity DataEC50:  2.93E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535384(CHEMBL4465344)copy SMILEScopy InChI
Affinity DataEC50:  1.97E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535385(CHEMBL4455475)copy SMILEScopy InChI
Affinity DataEC50:  670nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535386(CHEMBL4535914)copy SMILEScopy InChI
Affinity DataEC50:  3.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50535368(CHEMBL4450943)copy SMILEScopy InChI
Affinity DataEC50:  4.37E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HXKPubMed