Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50010395
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538416(CHEMBL4644835 | US11236045, Example 25)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538393(CHEMBL4647321 | US11236045, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538418(CHEMBL4641961 | US11236045, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538405(CHEMBL4642066)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538407(CHEMBL4647621 | US11236045, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538421(CHEMBL4649141 | US11236045, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538406(CHEMBL4640151)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538420(CHEMBL4636825 | US11236045, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538419(CHEMBL4646271)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538408(CHEMBL4634682)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538410(CHEMBL4649429)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538411(CHEMBL4646037)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538412(CHEMBL4643062)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538413(CHEMBL4637610)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538414(CHEMBL4644503)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538415(CHEMBL4635816)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538404(CHEMBL4636808)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538403(CHEMBL4649881)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538402(CHEMBL4641660)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538401(CHEMBL4649621)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538400(CHEMBL4643208)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538399(CHEMBL4643011)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538398(CHEMBL4640804)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538397(CHEMBL4633769)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538396(CHEMBL4633580)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538395(CHEMBL4634472)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538394(CHEMBL4640644)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538409(CHEMBL4644865)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538419(CHEMBL4646271)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538393(CHEMBL4647321 | US11236045, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538407(CHEMBL4647621 | US11236045, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538416(CHEMBL4644835 | US11236045, Example 25)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538418(CHEMBL4641961 | US11236045, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538420(CHEMBL4636825 | US11236045, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare Ltd.

Curated by ChEMBL
LigandPNGBDBM50538421(CHEMBL4649141 | US11236045, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WP2PubMed