Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50010555
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50113342(CHEMBL518383)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length GST-tagged human CDK2/Cyclin AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GST-tagged human CDK1/cyclin B expressed in SF-9 cells after 10 mins in presence of [gamma-33P]ATP by scintillation counter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant GST-tagged human CDK2/cyclin E expressed in SF-9 cells after 10 mins in presence of [gamma-33P]ATP by scintillation counter...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50113342(CHEMBL518383)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full length GST-tagged human CDK1/cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540078(CHEMBL4639890)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human CDK2/cyclin E after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human CDK2/cyclin A after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human CDK9/cyclin T after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 19(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540078(CHEMBL4639890)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50466842(CHEMBL1615221)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540077(CHEMBL4649135)copy SMILEScopy InChI
Affinity DataIC50: 321nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of GSK3alpha/beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540077(CHEMBL4649135)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of CDK9 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50330267(4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50330267(4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540080(CHEMBL4648857)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540077(CHEMBL4649135)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CDK1 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540077(CHEMBL4649135)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CDK7 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM148264(7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM148264(7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM60927(1-anilinonaphthalene-8-sulfonic acid | 8-Anilino-1...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM60927(1-anilinonaphthalene-8-sulfonic acid | 8-Anilino-1...)copy SMILEScopy InChI
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataKd:  53nMAssay Description:Binding affinity to CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540079(CHEMBL4632717)copy SMILEScopy InChI
Affinity DataKd:  5.40nMAssay Description:Binding affinity to CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540079(CHEMBL4632717)copy SMILEScopy InChI
Affinity DataKd:  0.310nMAssay Description:Binding affinity to CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-C(Homo sapiens (Human))
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540076(CHEMBL4649097)copy SMILEScopy InChI
Affinity DataKd:  10nMAssay Description:Binding affinity to CDK8/cyclin C (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB