Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50010636
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096921(3-[4-(1-Methyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096922(3-(1-Methyl-1H-indol-5-yl)-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096914(8-Methyl-3-(1-methyl-1H-indol-5-yl)-8-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096915(3-(1-Ethyl-1H-indol-5-yl)-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096913(3-(1-Ethyl-1H-indol-5-yl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096916(3-[4-(1-Benzyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096926(3-[4-(1-Ethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096919(8-Methyl-3-[4-(1-methyl-1H-pyrrol-2-yl)-phenyl]-8-...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096918(3-[4-(1,3-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-b...)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096923(3-[4-(1,5-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-b...)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096920(3-[4-(1-Benzyl-1H-pyrrol-2-yl)-phenyl]-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataKi:  59nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096925(3-[4-(1-Methyl-5-phenyl-1H-pyrrol-2-yl)-phenyl]-8-...)copy SMILEScopy InChI
Affinity DataKi:  112nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096924(3-[4-(1-Ethyl-1H-pyrrol-2-yl)-phenyl]-8-methyl-8-a...)copy SMILEScopy InChI
Affinity DataKi:  337nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096917(3-[4-(1,3-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-methy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096914(8-Methyl-3-(1-methyl-1H-indol-5-yl)-8-aza-bicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096913(3-(1-Ethyl-1H-indol-5-yl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096915(3-(1-Ethyl-1H-indol-5-yl)-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096922(3-(1-Methyl-1H-indol-5-yl)-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096916(3-[4-(1-Benzyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096920(3-[4-(1-Benzyl-1H-pyrrol-2-yl)-phenyl]-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096921(3-[4-(1-Methyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataIC50: 614nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096919(8-Methyl-3-[4-(1-methyl-1H-pyrrol-2-yl)-phenyl]-8-...)copy SMILEScopy InChI
Affinity DataIC50: 703nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096923(3-[4-(1,5-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-b...)copy SMILEScopy InChI
Affinity DataIC50: 825nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096926(3-[4-(1-Ethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096925(3-[4-(1-Methyl-5-phenyl-1H-pyrrol-2-yl)-phenyl]-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096917(3-[4-(1,3-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096924(3-[4-(1-Ethyl-1H-pyrrol-2-yl)-phenyl]-8-methyl-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50096918(3-[4-(1,3-Dimethyl-1H-pyrrol-2-yl)-phenyl]-8-aza-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+3nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M907ZRPubMed