Found 24 Enz. Inhib. hit(s) with all data for entry = 50010638 
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC6 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2HM5D0BPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2HM5D0BPubMedDrugBank
MMDB
PDB
3D Structure (crystal)Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant HDAC4 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant HDAC1 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human recombinant HDAC3 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of human recombinant HDAC2 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant HDAC4 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human recombinant HDAC5 using AMC-K(TFA)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
