Compile Data Set for Download or QSAR
Found 19 Enz. Inhib. hit(s) with all data for entry = 50010666
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097366(4-((1H-imidazol-1-yl)methyl)-1-nitro-4aH-xanthen-9...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097370(1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human testicular microsome Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097373(4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097367(1-Bromo-4-imidazol-1-ylmethyl-xanthen-9-one | 4-((...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097369(7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097363(1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human testicular microsome Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097365(1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human testicular microsome Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097368(8-((1H-imidazol-1-yl)methyl)-4-oxo-4H-chromene-5-c...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097364(3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097372(3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-phenyl-4H...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of human testicular microsome Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097370(1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097363(1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097362(8-((1H-imidazol-1-yl)methyl)-5-nitro-4H-chromen-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097371(5-Bromo-8-imidazol-1-ylmethyl-chromen-4-one | 8-((...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097365(1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097361(7-((4H-1,2,4-triazol-4-yl)methyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMedDrugBank