Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50011366
LigandPNGBDBM50155926(CHEMBL3183703)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 24nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of MSUMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of NLRP3 inflammasome activation in human THP1 cells assessed as inhibition of IL-1beta release in presence of nigericinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of NLRP3 (unknown origin) assessed as inhibition of IL-18 production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 35nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547440(CHEMBL4758640)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547444(CHEMBL4759516)copy SMILES
Affinity DataIC50: 76nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547452(CHEMBL4791679)copy SMILES
Affinity DataIC50: 79nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547450(CHEMBL4745667)copy SMILES
Affinity DataIC50: 93nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547441(CHEMBL4756798)copy SMILES
Affinity DataIC50: 96nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547446(CHEMBL4756693)copy SMILES
Affinity DataIC50: 126nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547448(CHEMBL4742825)copy SMILES
Affinity DataIC50: 142nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547442(CHEMBL4778322)copy SMILES
Affinity DataIC50: 164nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547439(CHEMBL4792478)copy SMILES
Affinity DataIC50: 208nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547451(CHEMBL4778164)copy SMILES
Affinity DataIC50: 243nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547455(CHEMBL4751187)copy SMILES
Affinity DataIC50: 294nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547449(CHEMBL4753623)copy SMILES
Affinity DataIC50: 306nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547453(CHEMBL4758006)copy SMILES
Affinity DataIC50: 344nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547447(CHEMBL4795321)copy SMILES
Affinity DataIC50: 369nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547457(CHEMBL4753197)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547461(CHEMBL4748040)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547443(CHEMBL4744515)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547454(CHEMBL4763529)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547456(CHEMBL4755384)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547462(CHEMBL4782757)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547458(CHEMBL4745706)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547459(CHEMBL4797652)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547460(CHEMBL4777050)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547445(CHEMBL4760079)copy SMILES
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed
LigandPNGBDBM50547438(CHEMBL4752523)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 (unknown origin) assessed as inhibition of TNFalpha production by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9402PubMed