Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 50011670
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549946(CHEMBL4796908)copy SMILES
Affinity DataIC50: 44nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549945(CHEMBL4784342)copy SMILES
Affinity DataIC50: 48nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549947(CHEMBL4749560)copy SMILES
Affinity DataIC50: 65nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549948(CHEMBL4792886)copy SMILES
Affinity DataIC50: 137nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataIC50: 660nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549946(CHEMBL4796908)copy SMILES
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549942(CHEMBL4748121)copy SMILES
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549947(CHEMBL4749560)copy SMILES
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549948(CHEMBL4792886)copy SMILES
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549945(CHEMBL4784342)copy SMILES
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549943(CHEMBL4743552)copy SMILES
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549941(CHEMBL4744343)copy SMILES
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549940(CHEMBL4796728)copy SMILES
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549942(CHEMBL4748121)copy SMILES
Affinity DataKd:  5.10E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549943(CHEMBL4743552)copy SMILES
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549941(CHEMBL4744343)copy SMILES
Affinity DataKd:  9.70E+4nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair