Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50011780
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551090(CHEMBL4748722)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50081717(CHEMBL3422338)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50081709(CHEMBL3422257)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551091(CHEMBL4792004)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551094(CHEMBL4757820)copy SMILES
Affinity DataIC50: 7nMAssay Description:Potentiation of amphotericin-induced cytotoxicity against human DU-145 cells over expressing CYP1B1 assessed as reversal of CYP1B1 mediated drug resi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551092(CHEMBL4749570)copy SMILES
Affinity DataIC50: 24nMAssay Description:Potentiation of amphotericin-induced cytotoxicity against human DU-145 cells over expressing CYP1B1 assessed as reversal of CYP1B1 mediated drug resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50081709(CHEMBL3422257)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551093(CHEMBL4763775)copy SMILES
Affinity DataIC50: 28nMAssay Description:Potentiation of amphotericin-induced cytotoxicity against human DU-145 cells over expressing CYP1B1 assessed as reversal of CYP1B1 mediated drug resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551095(CHEMBL4746654)copy SMILES
Affinity DataIC50: 37nMAssay Description:Potentiation of amphotericin-induced cytotoxicity against human DU-145 cells over expressing CYP1B1 assessed as reversal of CYP1B1 mediated drug resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50081717(CHEMBL3422338)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551090(CHEMBL4748722)copy SMILES
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551094(CHEMBL4757820)copy SMILES
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551092(CHEMBL4749570)copy SMILES
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551093(CHEMBL4763775)copy SMILES
Affinity DataIC50: 153nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551095(CHEMBL4746654)copy SMILES
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551091(CHEMBL4792004)copy SMILES
Affinity DataIC50: 885nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551095(CHEMBL4746654)copy SMILES
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551093(CHEMBL4763775)copy SMILES
Affinity DataIC50: 8.57E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551092(CHEMBL4749570)copy SMILES
Affinity DataIC50: 9.03E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551094(CHEMBL4757820)copy SMILES
Affinity DataIC50: 9.84E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551097(CHEMBL4787701)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551099(CHEMBL4745698)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551098(CHEMBL4786434)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551097(CHEMBL4787701)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551096(CHEMBL4751054)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551096(CHEMBL4751054)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))TBA
LigandPNGBDBM50551099(CHEMBL4745698)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50551098(CHEMBL4786434)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BG7PubMed