Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50011893
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111887(1-{3-[4-((Z)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111894(1-{3-[4-((E)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111881(1-{3-[4-((E)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.620nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111891(1-[3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111883(1-[3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111890(1-{8-((E)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111886(1-[3-(3-Fluoro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  7.30nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111880(1-{8-((Z)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111885(1-[3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111892(1-[3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50451492(CHEMBL2112943)copy SMILEScopy InChI
Affinity DataKi: >1.10E+3nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataIC50: 0.0770nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 0.0850nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111886(1-[3-(3-Fluoro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111891(1-[3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111883(1-[3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111885(1-[3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50451492(CHEMBL2112943)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111881(1-{3-[4-((E)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111892(1-[3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111887(1-{3-[4-((Z)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111894(1-{3-[4-((E)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 401nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111890(1-{8-((E)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)copy SMILEScopy InChI
Affinity DataIC50: 753nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111880(1-{8-((Z)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6515PubMed