Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50011984
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)copy SMILEScopy InChI
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-NLX from mouse MOR expressed in CHO cells incubated for 1.5 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50553073(CHEMBL4751167)copy SMILES
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-NLX from mouse MOR expressed in CHO cells incubated for 1.5 hrs by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50553072(CHEMBL4750948)copy SMILES
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-NLX from mouse MOR expressed in CHO cells incubated for 1.5 hrs by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50553072(CHEMBL4750948)copy SMILES
Affinity DataIC50: 62nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cells assessed as decrease in DAMGO-induced calcium influx incubated for 15 mins followed by DAMGO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50553073(CHEMBL4751167)copy SMILES
Affinity DataIC50: 133nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cells assessed as decrease in DAMGO-induced calcium influx incubated for 15 mins followed by DAMGO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50553072(CHEMBL4750948)copy SMILES
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at CXCR4 (unknown origin) expressed in HOS cells assessed as decrease in SDF1-induced calcium influx incubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50247128((6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells incubated for 40 mins by immunofluorescence assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50553072(CHEMBL4750948)copy SMILES
Affinity DataIC50: 1.72E+4nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells incubated for 40 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50247128((6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+4nMAssay Description:Antagonist activity at CXCR4 (unknown origin) expressed in HOS cells assessed as decrease in SDF1-induced calcium influx incubated for 15 mins follow...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50553074(CHEMBL4791514)copy SMILES
Affinity DataIC50: 7.40E+4nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells incubated for 40 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50553074(CHEMBL4791514)copy SMILES
Affinity DataIC50: 7.83E+4nMAssay Description:Antagonist activity at CXCR4 (unknown origin) expressed in HOS cells assessed as decrease in SDF1-induced calcium influx incubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WSDPubMed