Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50012200
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115988(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115989(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115998(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115995(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115991(2-(4-Acryloylamino-phenyl)-3-[(benzyl-methyl-amino...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115994(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115992(3-[(Benzyl-methyl-amino)-methyl]-2-[4-(cyclopropan...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115996(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115997(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115993(2-(4-Benzoylamino-phenyl)-3-[(benzyl-methyl-amino)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115990(3-[(Benzyl-methyl-amino)-methyl]-2-(4-butyrylamino...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed