Compile Data Set for Download or QSAR
Found 45 Enz. Inhib. hit(s) with all data for entry = 50012463
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50376383(CHEMBL259972)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50084631(CHEMBL3427203)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50096276(CHEMBL1235806)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557782(CHEMBL4800072)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557783(CHEMBL4784073)copy SMILES
Affinity DataIC50: 90nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557782(CHEMBL4800072)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557783(CHEMBL4784073)copy SMILES
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557784(CHEMBL4797035)copy SMILES
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557784(CHEMBL4797035)copy SMILES
Affinity DataIC50: 400nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50376383(CHEMBL259972)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50033277(CHEMBL3357103)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557785(CHEMBL4758829)copy SMILES
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557785(CHEMBL4758829)copy SMILES
Affinity DataIC50: 900nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557781(CHEMBL4788232)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557780(CHEMBL4755592)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557778(CHEMBL4745938)copy SMILES
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMedDrugBank
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557781(CHEMBL4788232)copy SMILES
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50084631(CHEMBL3427203)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557779(CHEMBL4761793)copy SMILES
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557778(CHEMBL4745938)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557780(CHEMBL4755592)copy SMILES
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557777(CHEMBL4757602)copy SMILES
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557777(CHEMBL4757602)copy SMILES
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50096276(CHEMBL1235806)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557779(CHEMBL4761793)copy SMILES
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50033277(CHEMBL3357103)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557780(CHEMBL4755592)copy SMILES
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 8.09E+4nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557784(CHEMBL4797035)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557783(CHEMBL4784073)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557782(CHEMBL4800072)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557781(CHEMBL4788232)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557785(CHEMBL4758829)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557778(CHEMBL4745938)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557777(CHEMBL4757602)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557779(CHEMBL4761793)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BP9PubMed