Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for entry = 50012491
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119524(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50104376(4-[5-(4-Fluoro-phenyl)-2-phenethyl-3H-imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119534(4-{5-(4-Fluoro-phenyl)-2-[3-(4-methanesulfinyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119505(4-[5-(4-Chloro-phenyl)-2-(4-methanesulfinyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119512(4-{5-(4-Fluoro-phenyl)-2-[2-(4-methanesulfinyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50114693(4-[5-(4-Fluoro-phenyl)-2-(3-methanesulfinyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119514(4-[5-(4-Fluoro-phenyl)-2-(3-methylsulfanyl-benzyls...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119507(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119521(4-[5-(4-Bromo-phenyl)-2-(4-methanesulfinyl-benzyls...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119511(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50114690(4-(2-(4-(methylsulfinyl)benzylthio)-4-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119518(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119536(4-[2-(4-Methanesulfinyl-benzylsulfanyl)-5-phenyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tübingen

Curated by ChEMBL
LigandPNGBDBM50119522(4-[2-Benzylsulfanyl-5-(4-fluoro-phenyl)-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2TGWPubMed