Compile Data Set for Download or QSAR
Found 90 Enz. Inhib. hit(s) with all data for entry = 50012510
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition EML4-ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558032(CHEMBL4798141)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50436850(CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition NMP-ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558034(CHEMBL4791252)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 38nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107097(US8592432, 83)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558035(CHEMBL4779222)copy SMILES
Affinity DataIC50: 47nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558028(CHEMBL4755518)copy SMILES
Affinity DataIC50: 150nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558026(CHEMBL4739938)copy SMILES
Affinity DataIC50: 186nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558022(CHEMBL4795530)copy SMILES
Affinity DataIC50: 212nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50436850(CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...)copy SMILEScopy InChI
Affinity DataIC50: 319nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558031(CHEMBL4780490)copy SMILES
Affinity DataIC50: 328nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 429nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 455nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of IGF-1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558031(CHEMBL4780490)copy SMILES
Affinity DataIC50: 684nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558035(CHEMBL4779222)copy SMILES
Affinity DataIC50: 700nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558032(CHEMBL4798141)copy SMILES
Affinity DataIC50: 703nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of HER1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
LigandPNGBDBM50558032(CHEMBL4798141)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558025(CHEMBL4749543)copy SMILES
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
LigandPNGBDBM50558035(CHEMBL4779222)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558026(CHEMBL4739938)copy SMILES
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558024(CHEMBL4762929)copy SMILES
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558030(CHEMBL4756013)copy SMILES
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558022(CHEMBL4795530)copy SMILES
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558024(CHEMBL4762929)copy SMILES
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558027(CHEMBL4787280)copy SMILES
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558026(CHEMBL4739938)copy SMILES
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558034(CHEMBL4791252)copy SMILES
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558024(CHEMBL4762929)copy SMILES
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558025(CHEMBL4749543)copy SMILES
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetInsulin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50558024(CHEMBL4762929)copy SMILES
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
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